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Year : 2017  |  Volume : 4  |  Issue : 1  |  Page : 33-37

To study the quality of life and its relation with socioeconomic status in thalassemic adolescents in a tertiary care center

1 MBBS Student, Christian Medical College and Hospital, Ludhiana, Punjab, India
2 Department of Physiology, Christian Medical College and Hospital, Ludhiana, Punjab, India
3 Department of Paediatrics, Christian Medical College and Hospital, Ludhiana, Punjab, India

Correspondence Address:
Navjot Kaur Grewal
House No: 35, Defence Colony, Bhai Randhir Singh Nagar, Ludhiana - 141 012, Punjab
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2348-3334.196062

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Background and Objectives: A large number of children are afflicted by thalassemia in India which may significantly impact their quality of life (QOL); hence, we hypothesized that there exists a strong relationship between socioeconomic status and QOL. We thus designed this study to assess QOL in adolescents diagnosed with β thalassemia major and its association with socioeconomic status. Further, we also compared the QOL and socioeconomic status between thalassemic and nonthalassemic adolescents. Materials and Methods: We recruited 35 adolescents diagnosed with β thalassemia major and 35 nonthalassemics in the age group of 10-18 years who matched in age, sex, and socioeconomic status. Selected cases and their parents were administered using PedsQL 4.0 India/Hindi questionnaire to assess QOL and modified Kuppuswamy scale to assess socioeconomic status. Results: Almost half of the thalassemic adolescents, i.e., 51.4% had poor QOL, whereas 48.6% of adolescents in control group had high QOL. There was no statistically significant association between QOL and socioeconomic status in both groups. It was observed that the difference between QOL and socioeconomic class though not significant but was more pronounced in study group (P = 0.114) than control group (P = 0.594). The receiver operating characteristic curve for QOL parameters indicated that social domain was the major contributor to poor QOL in thalassemics. Conclusion: Our study showed that thalassemic adolescents had significantly poor QOL, social domain being the major contributor as compared to nonthalassemics. We propose that provision of subsidized organized care can negate the impact of poor socioeconomic status on QOL of thalassemics.

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