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ORIGINAL ARTICLE
Year : 2017  |  Volume : 4  |  Issue : 2  |  Page : 94-98

Prescribing pattern and cost analysis of antihypertensives in India


1 Drug Safety Associate, Bioclinica Safety and Regulatory Solutions, Mysore, Karnataka, India
2 Department of Pharmacy Practice, Raghavendra Institute of Pharmaceutical Education and Research, Anantapuramu, Andhra Pradesh, India
3 Department of Pharmacy Practice, Nirmala College of Pharmacy, Guntur, Andhra Pradesh, India
4 Department of Pharmacy Practice, A. M. Reddy Memorial College of Pharmacy, Guntur, Andhra Pradesh, India
5 Department of Pharmacy Practice, St. James College of Pharmaceutical Sciences, Thrissur, Kerala, India

Correspondence Address:
Mohanraj Rathinavelu Mudhaliar
Division of Pharmacy Practice, Centre for Pharmaceutical Research, Raghavendra Institute of Pharmaceutical Education and Research, Anantapuramu, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2348-3334.201995

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Background: Hypertension has been reported to be the strongest modifiable global risk factor for cardiovascular morbidity, mortality as well as health burdens. Antihypertensive pharmacotherapy effectively reduces hypertension-related morbidity and mortality. Prescribing pattern surveys are one of the drug use evaluation techniques providing an unbiased picture and identification of suboptimal prescribing patterns. Objective: The 6-month cross-sectional study was designed to assess the prescription pattern and cost of antihypertensives therapy in a health-care resource-limited setting of India. Materials and Methods: The hypertensive patients were divided into two groups according to risk assessment using the World Health Organization and International Society of Hypertension guidelines for the management of hypertension. The average drug acquisition and the percentage expenditure costs were calculated for each drug class on a daily and annual basis, and InStat GraphPad Prism was the statistical tool used. Results: In our study of 100 patients, the most commonly prescribed antihypertensives were calcium channel blockers in 49.81% and beta-blockers in 12.73% patients, respectively. The cost analysis on antihypertensive medications utilized showed a total expenditure of Rs. 3823.58 invested in 1 year. Conclusion: The drug use pattern of antihypertensives was evidenced based but imposed economic burden in patients. Hence, rational use of generic medications was recommended.


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